Alzheimer's Disease Research Today is a free monthly online journal that collates and summarizes the latest research about Alzheimer's Disease, including details on diagnosis, memory loss, heredity, treatment, medication.

Physical activity and white matter lesion progression: assessment using MRI.

Podewils LJ, Guallar E, Beauchamp N, Lyketsos CG, Kuller LH, Scheltens P

Department of Epidemiology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. lpp8@cdc.gov

We evaluated the association between physical activity and changes in white matter lesions (WMLs) on MRI in a sample of 179 older adults comprising 59 incident cases of Alzheimer disease, 60 persons with mild cognitive impairment, and 60 persons who remained cognitively stable over a median 5-year follow-up. Physical activity was not significantly associated with a decreased rate of periventricular or deep WML progression.

Published 10 April 2007 in Neurology, 68(15): 1223-6.
Full-text of this article is available online (may require subscription).

© 2004-2008 Alzheimer's Disease Research Today. All Rights Reserved.