Alzheimer's Disease Research Today is a free monthly online journal that collates and summarizes the latest research about Alzheimer's Disease, including details on diagnosis, memory loss, heredity, treatment, medication.

Volume 4 (2007), Issue 11 (November)

1. Association between apolipoprotein E4 and cognitive decline in elderly adults.
   J Am Geriatr Soc, 55(11): 1777-85. [Abstract] [Full-text]
2. The effect of ambient bright light therapy on depressive symptoms in persons with dementia.
   J Am Geriatr Soc, 55(11): 1817-24. [Abstract] [Full-text]
3. Dementia undiagnosed in poor older adults with functional impairment.
   J Am Geriatr Soc, 55(11): 1771-6. [Abstract] [Full-text]
4. Cost-benefit analysis of second-generation antipsychotics and placebo in a randomized trial of the treatment of psychosis and aggression in Alzheimer disease.
   Arch Gen Psychiatry, 64(11): 1259-68. [Abstract] [Full-text]
5. Relation of cognitive activity to risk of developing Alzheimer disease.
   Neurology, 69(20): 1911-20. [Abstract] [Full-text]
6. Alzheimer's disease peptide epitope vaccine reduces insoluble but not soluble/oligomeric Abeta species in amyloid precursor protein transgenic mice.
   J Neurosci, 27(46): 12721-31. [Abstract] [Full-text]
7. 1-(3',4'-Dichloro-2-fluoro[1,1'-biphenyl]-4-yl)-cyclopropanecarboxylic acid (CHF5074), a novel gamma-secretase modulator, reduces brain beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease without causing peripheral toxicity.
   J Pharmacol Exp Ther, 323(3): 822-30. [Abstract] [Full-text]
8. Apolipoprotein E genotype influences vertical transmission of herpes simplex virus type 1 in a gender specific manner.
   Aging Cell, 6(6): 841-2. [Abstract] [Full-text]
9. Evaluation of reference regions for (R)-[(11)C]PK11195 studies in Alzheimer's disease and mild cognitive impairment.
   J Cereb Blood Flow Metab, 27(12): 1965-74. [Abstract] [Full-text]
10. Single particle detection of Abeta aggregates associated with Alzheimer's disease.
    Biochem Biophys Res Commun, 364(4): 902-7. [Abstract] [Full-text]
11. A novel mutation in the PSEN1 gene (L286P) associated with familial early-onset dementia of Alzheimer type and lobar haematomas.
    Eur J Neurol, 14(12): 1409-12. [Abstract] [Full-text]
12. Automated cortical thickness measurements from MRI can accurately separate Alzheimer's patients from normal elderly controls.
    Neurobiol Aging, 29(1): 23-30. [Abstract] [Full-text]
13. Conversion from cognitive health to mild cognitive impairment and Alzheimer's disease: prediction by plasma amyloid beta 42, medial temporal lobe atrophy and homocysteine.
    Neurobiol Aging, 29(1): 1-11. [Abstract] [Full-text]
14. Proteomic identification of brain proteins in the canine model of human aging following a long-term treatment with antioxidants and a program of behavioral enrichment: relevance to Alzheimer's disease.
    Neurobiol Aging, 29(1): 51-70. [Abstract] [Full-text]
15. Cathepsin D expression is decreased in Alzheimer's disease fibroblasts.
    Neurobiol Aging, 29(1): 12-22. [Abstract] [Full-text]
16. Novel strategies for Alzheimer's disease treatment.
    Expert Opin Biol Ther, 7(12): 1853-67. [Abstract] [Full-text]
17. Imaging of amyloid plaques and cerebral glucose metabolism in semantic dementia and Alzheimer's disease.
    Neuroimage, 39(2): 619-33. [Abstract] [Full-text]
18. Influence of galantamine on vasomotor reactivity in Alzheimer's disease and vascular dementia due to cerebral microangiopathy.
    Stroke, 38(12): 3186-92. [Abstract] [Full-text]
19. Progressive increase in infarct size, neuroinflammation, and cognitive deficits in the presence of high levels of amyloid.
    Stroke, 38(12): 3245-50. [Abstract] [Full-text]
20. Cystatin C inhibits amyloid-beta deposition in Alzheimer's disease mouse models.
    Nat Genet, 39(12): 1440-2. [Abstract] [Full-text]
21. Progesterone and estrogen regulate Alzheimer-like neuropathology in female 3xTg-AD mice.
    J Neurosci, 27(48): 13357-65. [Abstract] [Full-text]
22. Enhanced accumulation of phosphorylated alpha-synuclein and elevated beta-amyloid 42/40 ratio caused by expression of the presenilin-1 deltaT440 mutant associated with familial Lewy body disease and variant Alzheimer's disease.
    J Neurosci, 27(48): 13092-7. [Abstract] [Full-text]

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