Alzheimer's Disease Research Today is a free monthly online journal that collates and summarizes the latest research about Alzheimer's Disease, including details on diagnosis, memory loss, heredity, treatment, medication.

Volume 4 (2007), Issue 1 (January)

1. Diffusion tensor imaging of cingulum fibers in mild cognitive impairment and Alzheimer disease.
   Neurology, 68(1): 13-9. [Abstract] [Full-text]
2. Is alpha-T catenin (VR22) an Alzheimer's disease risk gene?
   J Med Genet, 44(1): e63. [Abstract] [Full-text]
3. The presenilin hypothesis of Alzheimer's disease: evidence for a loss-of-function pathogenic mechanism.
   Proc Natl Acad Sci U S A, 104(2): 403-9. [Abstract] [Full-text]
4. Immunohistochemical localization of dopamine receptor subtypes (D1R-D5R) in Alzheimer's disease brain.
   Brain Res, 1131(1): 187-96. [Abstract] [Full-text]
5. Anatomically constrained region deformation for the automated segmentation of the hippocampus and the amygdala: Method and validation on controls and patients with Alzheimer's disease.
   Neuroimage, 34(3): 996-1019. [Abstract] [Full-text]
6. Multivariate network analysis of fiber tract integrity in Alzheimer's disease.
   Neuroimage, 34(3): 985-95. [Abstract] [Full-text]
7. Education and Alzheimer disease without dementia: support for the cognitive reserve hypothesis.
   Neurology, 68(3): 223-8. [Abstract] [Full-text]
8. Serum response factor and myocardin mediate arterial hypercontractility and cerebral blood flow dysregulation in Alzheimer's phenotype.
   Proc Natl Acad Sci U S A, 104(3): 823-8. [Abstract] [Full-text]
9. Idiopathic normal-pressure hydrocephalus: clinical comorbidity correlated with cerebral biopsy findings and outcome of cerebrospinal fluid shunting.
   J Neurol Neurosurg Psychiatry, 78(2): 157-61. [Abstract] [Full-text]
10. The effect of the apolipoprotein E gene polymorphisms and haplotypes on behavioural and psychological symptoms in probable Alzheimer's disease.
    J Neurol Neurosurg Psychiatry, 78(2): 123-6. [Abstract] [Full-text]
11. Magnetic resonance imaging of Alzheimer's pathology in the brains of living transgenic mice: a new tool in Alzheimer's disease research.
    Neuroscientist, 13(1): 38-48. [Abstract] [Full-text]
12. Impaired spatial learning in the APPSwe + PSEN1DeltaE9 bigenic mouse model of Alzheimer's disease.
    Genes Brain Behav, 6(1): 54-65. [Abstract] [Full-text]
13. Increased level of active GSK-3beta in Alzheimer's disease and accumulation in argyrophilic grains and in neurones at different stages of neurofibrillary degeneration.
    Neuropathol Appl Neurobiol, 33(1): 43-55. [Abstract] [Full-text]
14. The novel gamma secretase inhibitor N-[cis-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoromethanesulfonamide (MRK-560) reduces amyloid plaque deposition without evidence of notch-related pathology in the Tg2576 mouse.
    J Pharmacol Exp Ther, 320(2): 552-8. [Abstract] [Full-text]
15. Conversion from subtypes of mild cognitive impairment to Alzheimer dementia.
    Neurology, 68(4): 288-91. [Abstract] [Full-text]
16. Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide.
    Nat Rev Mol Cell Biol, 8(2): 101-12. [Abstract] [Full-text]
17. Bim is elevated in Alzheimer's disease neurons and is required for beta-amyloid-induced neuronal apoptosis.
    J Neurosci, 27(4): 893-900. [Abstract] [Full-text]
18. Disturbed cross talk between insulin-like growth factor I and AMP-activated protein kinase as a possible cause of vascular dysfunction in the amyloid precursor protein/presenilin 2 mouse model of Alzheimer's disease.
    J Neurosci, 27(4): 824-31. [Abstract] [Full-text]
19. Abeta oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease.
    J Neurosci, 27(4): 796-807. [Abstract] [Full-text]
20. Learning decreases A beta*56 and tau pathology and ameliorates behavioral decline in 3xTg-AD mice.
    J Neurosci, 27(4): 751-61. [Abstract] [Full-text]
21. Cerebrospinal fluid tau, phospho-tau181 and beta-amyloid1-42 in idiopathic normal pressure hydrocephalus: a discrimination from Alzheimer's disease.
    Eur J Neurol, 14(2): 168-73. [Abstract] [Full-text]
22. The structure of the Alzheimer amyloid beta 10-35 peptide probed through replica-exchange molecular dynamics simulations in explicit solvent.
    J Mol Biol, 366(1): 275-85. [Abstract] [Full-text]
23. Memantine in the treatment of mild-to-moderate Alzheimer's disease.
    Expert Opin Pharmacother, 8(2): 203-14. [Abstract] [Full-text]
24. Patterns of neuropsychological impairment in frontotemporal dementia.
    Neurology, 68(5): 369-75. [Abstract] [Full-text]
25. Microglial transplantation increases amyloid-beta clearance in Alzheimer model rats.
    FEBS Lett, 581(3): 475-8. [Abstract] [Full-text]
26. Cerebrospinal fluid of Alzheimer's disease and dementia with Lewy bodies patients enhances alpha-synuclein fibril formation in vitro.
    Exp Neurol, 203(2): 579-83. [Abstract] [Full-text]
27. An easy Z-score imaging system for discrimination between very early Alzheimer's disease and controls using brain perfusion SPECT in a multicentre study.
    Nucl Med Commun, 28(3): 199-205. [Abstract] [Full-text]
28. Comparative multiresolution wavelet analysis of ERP spectral bands using an ensemble of classifiers approach for early diagnosis of Alzheimer's disease.
    Comput Biol Med, 37(4): 542-58. [Abstract] [Full-text]

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