Alzheimer's Disease Research Today is a free monthly online journal that collates and summarizes the latest research about Alzheimer's Disease, including details on diagnosis, memory loss, heredity, treatment, medication.

Reduction of optic nerve fibers in patients with Alzheimer disease identified by laser imaging.

Danesh-Meyer HV, Birch H, Ku JY, Carroll S, Gamble G

Department of Ophthalmology, University of Auckland, Auckland. New Zealand. h.daneshmeyer@auckland.ac.nz

In this case-control study, we compared the optic nerves (ONs) by clinical examination and scanning laser ophthalmoscopy (SLO) of 40 patients with Alzheimer disease (AD) and 50 controls. There was a reduction in the number of ON fibers in patients with AD, with a threefold greater odds ratio for a larger optic cup-to-disc ratio in patients with AD.

Published 28 November 2006 in Neurology, 67(10): 1852-4.
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